Hepatitis b virus infection its sequelae and prevention by vaccination




















Figure 1. Ann Epidemiol 19 : — Incidence of hepatitis B virus infections in preschool children in Taiwan. J Infect Dis : — Incidence of hepatitis among students at a university in Taiwan. Am J Epidemiol : — Efficacy of hepatitis B immune globulin for prevention of perinatal transmission of the hepatitis B virus carrier state: Final report of a randomized double-blind, placebo-controlled trial. Hepatology 3 : — Prevention of perinatally transmitted hepatitis B virus infections with hepatitis B immune globulin and hepatitis B vaccine.

Lancet 2 : — Ann Intern Med 66 : — Australia antigen and hepatitis. JAMA : — Vaccine against human hepatitis B. Fulminant hepatitis in children in Taiwan: The important role of hepatitis B virus.

J Pediatr : 34— Maternal transmission of hepatitis B virus in childhood HCC. Cancer 64 : — Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children.

N Engl J Med : — Decreased incidence of hepatocellular carcinoma in hepatitis B vaccinees: A year follow-up study. J Natl Cancer Inst : — Ling-term protection of hepatitis B vaccine: Lessons from Alaskan experience after 15 years. Ann Intern Med : — Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B. J Hepatol 50 : — Fighting against hepatitis B: Lessons from Taiwan.

Hepatology 54 : — Seroepidemiology of hepatitis B virus infection in children: Ten years of mass vaccination in Taiwan. Effects of maternal screening and universal immunization to prevent mother-to-infant transmission of HBV. Gastroenterology : — Boosters for hepatitis B vaccination? Need for an evidence-based policy. Hepatology 51 : — A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection.

J Hepatol 55 : — Yeast recombinant hepatitis B vaccine. Infection 15 : 3—7. Association of hepatitis B surface antigenemia and membranous nephropathy in children in Taiwan. Clin Nephrol 20 : — Baseline seroepidemiology of hepatitis B virus infection in children in Taipei, A study just before mass hepatitis B vaccination program in Taiwan. J Med Virol 18 : — Efficacy of a mass hepatitis B vaccination program in Taiwan: Studies on infants of hepatitis B surface antigen-carrier mothers.

No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization. Long-term follow-up of children with postnatal immunoprophylaxis failure who were infected with hepatitis B virus surface antigen gene mutant. Determination of immune memory to hepatitis B vaccination through early booster response in college students.

Universal hepatitis B vaccination: Killing 2 birds with 1 stone. Am J Med : — Universal hepatitis B vaccination and the decreased mortality from fulminant hepatitis in infants in Taiwan. J Pediatr : — Extrahepatic manifestations of acute hepatitis B virus infection. Gastroenterol Hepatol 9 : — The immune response to hepatitis B vaccine in humans: Inheritance patterns in families. J Exp Med : — Viral hepatitis: Global goals for vaccination. J Clin Virol 55 : — Immunogenicity of hepatitis B virus vaccine in healthy Chinese neonates.

The protective efficacy of recombinant hepatitis B vaccine in newborn infants of hepatitis B e antigen-positive-hepatitis B surface antigen carrier mothers. Pediatr Infect Dis J 10 : — Lancet Oncol 14 : — Universal hepatitis B vaccination reduces childhood hepatitis B virus-associated membranous nephropathy. Pediatrics : e—e Abstract Worldwide, hepatitis B virus HBV infection is a major cause of acute and chronic hepatitis, cirrhosis and hepatocellular cancer.

Publication types Review. Substances Hepatitis B Vaccines. Intrauterine transmission of hepatitis B virus is closely related to placental leakage. Hyams KC. Risks of chronicity following acute hepatitis B virus infection: a review.

Clin Infect Dis. Alter MJ. Epidemiology and prevention of hepatitis B. Alter M, Mast E. The epidemiology of viral hepatitis in the United States. Gastroenterol Clin North Am. Etiological investigation of acute post-transfusion non-A, non-B hepatitis in China.

Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol. Comparison of the amino acid sequences of nine different serotypes of hepatitis B surface antigen and genomic classification of the corresponding hepatitis B virus strains. A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness.

Establishment of a method for classification of HBV genome and it's application. Chin J Exp Clin Virol. Virus Genes. A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotype B and C. Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers. Hepatitis B virus genotype distribution among chronic hepatitis B virus carriers in Shanghai, China.

Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Hepatitis B genotypes and the response to interferon therapy. Genetic characteristics of hepatitis B virus and response to interferon-alfa treatment. Prevalence of naturally occurring surface gene variants of hepatitis B virus in non-immunized surface antigen-negative Chinese carriers.

Hu KQ. Occult hepatitis B virus infection and its clinical implications. J Viral Hepat. Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen.

Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely "occult"? World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants.

Clinical and histological characteristics of chronic hepatitis B with negative hepatitis B e-antigen. Chin Med J Engl ; — Hepatitis B e antigen-negative chronic hepatitis B in Hong Kong. Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Genotypes, nt, and geographic origin of hepatitis B virus-large-scale analysis using a new genotyping method.

Magnius LO, Norder H. Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication.

J Virol. French Multicentre Group. Hadziyannis S. Viral Hepatitis Rev. Hepatocellular carcinoma and hepatitis B virus: a prospective study of 22 men in Taiwan. The relation of hepatocellular carcinoma to infection with hepatitis B and related viruses in man and animals. Epidemiological characteristics and risk factors of hepatocellular carcinoma. J Gastroenterol Hepatol. Epidemiology of primary liver cancer. Hepatitis B virus e antigen and primary hepatocellular carcinoma.

Anticancer Res. Additive effect modification of hepatitis B surface antigen and e antigen on the development of hepatocellular carcinoma. Br J Cancer. New Engl J Med. High viral loads, serum alanine aminotransferase and gender are predictive factors for the development of hepatocellular carcinoma from viral compensated liver cirrhosis. A nested case-control study using 96 untreated patients. High viral load is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

Yeast-recombinant hepatitis B vaccine: Efficacy with hepatitis B immune globulin in prevention of perinatal hepatitis B virus transmission. A randomized control trial on interruption of HBV transmission in uterus. Terrault NA, Vyas G. Hepatitis B immune globulin preparations and use in liver transplantation. Clin Liver Dis. Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures.

Hepatitis B virus infection in children and adolescents in a hyperendemic area: 15 years after mass hepatitis B vaccination. Ann Intern Med. Seroepidemiology of hepatitis B virus infection in children: Ten years of mass vaccination in Taiwan.

A mass vaccination program in Taiwan against hepatitis B virus infection in infants of hepatitis B surface antigen-carrier mothers. Efficacy of a mass hepatitis B vaccination program in Taiwan. Studies on infants of hepatitis B surface antigen-carrier mothers. Long - term evaluation of immune efficacy among newborns 16 Years after HBV vaccination. Additional Resources Recent Publications: Hepatitis B surface antigen seroprevalence among children in the Philippines external icon.

Social and behavioral determinants of attitudes towards and practices of hepatitis B vaccine birth dose in Vietnam external icon. An approach for preparing and responding to adverse events following immunization reported after hepatitis B vaccine birth dose administration external icon.

Prevalence of chronic hepatitis B virus infection among children in Haiti, external icon. Progress toward hepatitis B control and elimination of mother-to-child transmission of hepatitis B virus — Western Pacific Region, — The status of hepatitis B control in the African Region external icon. Hepatitis B vaccine birth dose coverage correlates worldwide with rates of institutional deliveries and skilled attendance at birth external icon. Improving hepatitis B birth dose coverage through village health volunteer training and pregnant women education external icon.

Evaluation of storing hepatitis B vaccine outside the cold chain in the Solomon Islands: identifying opportunities and barriers to implementation external icon. Hepatitis B virus infection among pregnant women in Haiti: a cross-sectional serosurvey external icon.



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